DNA sequences

Zero in on computational challenges in Nanopore sequencing

Xin Gao, Professor, Computer Science

Sep 2, 12:00 - 13:00

B9 L2 H1

bioinformatics machine learning Nanopore Sequencing DNA sequences

In this talk, I will first give an overview of the research activities in Structural and Functional Bioinformatics Group (http://sfb.kaust.edu.sa). I will then focus on our efforts on developing computational methods to tackle key open problems in Nanopore sequencing. In particular, I will introduce our recent works on developing a collection of computational methods to decode raw electrical current signal sequences into DNA sequences, to simulate raw signals of Nanopore, and to efficiently and accurately align electrical current signal sequences with DNA sequences. Then, I will further introduce their applications in clinical and environmental fields.